James Harrison, whose unique blood plasma saved over 2.4 million newborns, has passed away at 88. 

Known as the “man with the golden arm,” Harrison had an exceptionally rare antibody, Anti-D, which is used to prevent a deadly condition in unborn babies.

His family confirmed that he died in his sleep on 17 February in New South Wales.

Harrison’s daughter, Tracey Mellowship, said her father was always eager to donate, believing that “the life you save could be your own.”

Harrison’s journey as a donor began after he underwent major chest surgery at 14 and received numerous blood transfusions. 

Determined to give back, he started donating at 18 and continued for over six decades. 

In 2005, he set a world record for blood plasma donations, a record he held until 2022.

His contributions were crucial in preventing haemolytic disease of the foetus and newborn (HDFN), a potentially fatal condition that once claimed the lives of half the babies diagnosed with it.

There are fewer than 200 Anti-D donors in Australia, but they collectively help an estimated 45,000 mothers and babies annually. 

Researchers at Lifeblood and the Walter and Eliza Hall Institute of Medical Research are now working on a breakthrough—growing Anti-D antibodies in the lab to ensure a sustainable supply for future generations.

Lifeblood’s research director, David Irving, described the development of lab-made Anti-D as a “holy grail” due to the scarcity of suitable donors.